Host: Rabbit
Target Protein: villin
IR: Immunogen Range:
Clonality:
Isotype: IgG
Entrez Gene: 7429
Swiss Prot: P09327
Source: Recombinant human villin protein:
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Villin can cap, nucleate, sever and bundle actin in a calcium and phosphoinositide regulated manner. It is associated with the microvillar actin core bundle of intestinal and renal brush border implicated in adsorption. Villin is composed of six repeats, each containing 150 residues that together constitute the core domain followed by the carboxyl terminal headpiece domain of 87 residues. The core domain retains the calcium dependent capping nucleating and severing activity, whereas the headpiece domain contributes towards actin filament bundling and binding F actin, independently of Calcium.
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-1000, IHC-P=1:20-200, IHC-F=1:20-200, ICC=1:100-500, IF=1:50-200
Cross Reactive Species: Rat,Mouse,Human
For research use only. Not intended for diagnostic or therapeutic use.