Host: Rabbit
Target Protein: CD8
IR: Immunogen Range:41-140/236
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 24930
Swiss Prot: P07725
Source:
KLH conjugated synthetic peptide derived from rat CD8:41-140/236
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000
Cross Reactive Species: Rat
For research use only. Not intended for diagnostic or therapeutic use.