Host: Rabbit
Target Protein: ATF4
IR: Immunogen Range:
Clonality:
Isotype: IgG
Entrez Gene: 468
Swiss Prot: P18848
Source: KLH conjugated synthetic peptide derived from human ATF4:
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011]
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-1000, IHC-P=1:50-200, IHC-F=1:50-200, ICC=1:50, IF=1:50-200, Flow-Cyt=1:50
Cross Reactive Species: Human,Rat (predicted: Mouse)
For research use only. Not intended for diagnostic or therapeutic use.