bs-55203R [Primary Antibody]
Rabbit  Anti-SMARCA4  Polyclonal Antibody
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Host: Rabbit

Target Protein: SMARCA4

IR: Immunogen Range:30-130/1647

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6597

Swiss Prot: P51532

Source: KLH conjugated synthetic peptide derived from human SMARCA4:30-130/1647 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Background: The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Alternatively spliced transcripts have been found for this gene, but their full-length natures have not been determined.

Size: 200ul

Concentration: 1mg/ml

Applications: WB=1:500-2000, IHC-P=1:50-100, ICC=1:100

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

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