Host: Rabbit
Target Protein: ACE2
IR: Immunogen Range:
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 59272
Swiss Prot: Q9BYF1
Source: KLH conjugated synthetic peptide derived from human ACE2:
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Background: The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008].
Size: 200ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:400-800, IHC-F=1:400-800, ELISA=1:5000-10000
Cross Reactive Species: Rat,Mouse,Human
For research use only. Not intended for diagnostic or therapeutic use.