Host: Rabbit
Target Protein: PDX1
IR: Immunogen Range:
Clonality:
Isotype: IgG
Entrez Gene: 3651
Swiss Prot: P52945
Source: Recombinant human PDX1 protein:
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (IDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Aug 2017]
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-1000, IHC-P=1:50-200, IHC-F=1:50-200, ICC=1:50-200, IF=1:50-200
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.