Host: Rabbit
Target Protein: ATM
IR: Immunogen Range:
Clonality:
Isotype: IgG
Entrez Gene: 472
Swiss Prot: Q62388
Source: KLH conjugated synthetic peptide derived from human ATM:
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: ATM is a 370 kDa nuclear phosphoprotein involved in the autosomal recessive disease Ataxia Telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation, apoptosis, and response to DNA damage repair (DNA damage caused by such things as ionizing irradiation activates ATM kinase). The C terminal region has extensive homology to the catalytic domains of Phosphatidylinositol 3 kinases (PI3 kinases).
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:50-200, ICC=1:50, IF=1:50-200
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.