bs-0568R [Primary Antibody]
Rabbit  Anti-CDK6  Polyclonal Antibody
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Host: Rabbit

Target Protein: CDK6

IR: Immunogen Range:21-110/326

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1021

Swiss Prot: Q00534

Source: KLH conjugated synthetic peptide derived from human CDK6:21-110/326 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb.

Size: 200ul

Concentration: 1mg/ml

Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=1ug/test, ELISA=1:5000-10000

Cross Reactive Species: Human,Mouse,Rat (predicted: Dog,Cow,Horse)

For research use only. Not intended for diagnostic or therapeutic use.

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