Host: Rabbit
Target Protein: NADPH oxidase 4
IR: Immunogen Range:C-terminal
Clonality:
Isotype: IgG
Entrez Gene: 50507
Swiss Prot: Q9JHI8
Source: Recombinant human NADPH oxidase 4 :C-terminal
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Nox4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. Nox4 is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Like gp91-phox, the enzymatic activity of Nox4 produces superoxide anions. In vascular cells, the addition of angiotensin II increases Nox4 expression, which suggests a role for Nox-4 in vascular oxidative stress response.
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:1000, IHC-P=1:50-200, ICC=1:50
Cross Reactive Species: Human,Mouse,Rat
For research use only. Not intended for diagnostic or therapeutic use.