Host: Mouse

Target Protein: SARS-CoV-2 (2019-nCoV) Nucleocapsid

IR: Immunogen Range:full length

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 43740575

Swiss Prot: P0DTC9

Source: Recombinant SARS-CoV-2 (2019-nCoV) Nucleocapsid protein:full length 

Purification: Affinity purified by Protein A

Storage: 0.01M PBS(pH7.4) with 0.03% Proclin300 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. Human Gene ID : SARS-CoV-2 N