Host: Mouse
Target Protein: GBA
IR: Immunogen Range:301-400/536
Clonality: Monoclonal
Isotype: IgM
Entrez Gene: 2629
Swiss Prot: P04062
Source: KLH conjugated synthetic peptide derived from human GBA:301-400/536
Purification: affinity purified by Protein G
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000
Cross Reactive Species: (predicted: Human,Pig,Cow)
For research use only. Not intended for diagnostic or therapeutic use.