Host: Mouse

Target Protein: EIF2B3

IR: Immunogen Range:151-400/452

Clonality: Monoclonal

Isotype: IgG1,k

Entrez Gene: 8891

Swiss Prot: Q9NR50

Source: KLH conjugated synthetic peptide derived from human EIF2B3:151-400/452 

Purification: affinity purified by Protein G

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]