Host: Mouse
Target Protein: EIF2B3
IR: Immunogen Range:151-400/452
Clonality: Monoclonal
Isotype: IgG1,k
Entrez Gene: 8891
Swiss Prot: Q9NR50
Source: KLH conjugated synthetic peptide derived from human EIF2B3:151-400/452
Purification: affinity purified by Protein G
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:25, ICC=1:25, IF=1:25
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.