Host: Mouse
Target Protein: TSG101
IR: Immunogen Range:
Clonality: Monoclonal
Isotype: IgG1,κ
Entrez Gene: 7251
Swiss Prot: Q99816
Source: Recombinant human TSG101.:
Purification: affinity purified by Protein G
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.