Host: Rabbit
Target Protein: SLAMF6/LY108
IR: Immunogen Range:51-150/331
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 30925
Swiss Prot: Q9ET39
Source: KLH conjugated synthetic peptide derived from mouse SLAMF6:51-150/331
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: SLAMF6 is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. It may play a role in the regulation of autoimmune diseases.
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, ELISA=1:5000-10000
Cross Reactive Species: Mouse (predicted: Rat)
For research use only. Not intended for diagnostic or therapeutic use.