Host: Rabbit

Target Protein: phospho-Caldesmon (Ser789)

IR: Immunogen Range:VT(p-S)PT

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 800

Swiss Prot: Q05682

Source: KLH conjugated Synthesised phosphopeptide derived from human Caldesmon around the phosphorylation site of Ser789:VT(p-S)PT 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jul 2008].