Host: Rabbit
Target Protein: SIGLEC5
IR: Immunogen Range:481-551/551
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 8778
Swiss Prot: O15389
Source:
KLH conjugated synthetic peptide derived from human CD170:481-551/551
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha2,3-linked and alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. This molecule is expressed by monocytic/myeloid lineage cells. Found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. Expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differenciation.
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=1μg /test, ELISA=1:5000-10000
Cross Reactive Species: Human (predicted: Mouse,Rat,Pig,Cow,Horse,Rabbit)
For research use only. Not intended for diagnostic or therapeutic use.