Host: Rabbit

Target Protein: LYRIC

IR: Immunogen Range:131-230/582

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 92140

Swiss Prot: Q86UE4

Source: KLH conjugated synthetic peptide derived from human AEG-1:131-230/582 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: LYRIC is a type II membrane protein, the precise role of which has yet to be defined. It is expressed in breast and prostate carcinoma and is a potential mediator of lung metastasis. It has also been found in mouse Purkinje neurons and cerebellum. In epithelial cells it is recruited to tight junctions (TJ) during the maturation of the TJ complexes. LYRIC co-localizes with beta-catenin in normal and tumour tissues.