Host: Rabbit
Target Protein: ULBP3
IR: Immunogen Range:101-200/244
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 79465
Swiss Prot: Q9BZM4
Source: KLH conjugated synthetic peptide derived from human ULBP3:101-200/244
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: ULBP3 is a human ligand for the NKG2D receptor, together with at least ULBP1 and ULBP2. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. ULBP3 has a lower affinity for NKG2D compared to ULBP1 and ULBP2 and induces weaker signaling responses than does ULBP2 or ULBP1.
Size: 50ul
Concentration: 1mg/ml
Applications: IHC-F=1:100-500, IF=1:100-500
Cross Reactive Species: (predicted: Human)
For research use only. Not intended for diagnostic or therapeutic use.