Host: Mouse
Target Protein: human CD11b
IR: Immunogen Range:
Clonality: Monoclonal
Isotype: Mouse IgG1, k
Entrez Gene: 3684
Swiss Prot: P11215
Source: Recombinant human CD11b:
Purification: Affinity purified by Protein G
Storage: 0.01M TBS(pH=7.4) Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Size: 100ug
Concentration: 1mg/ml
Applications: Flow-Cyt=1ug/Test, ELISA=1:5000-10000
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.