Host: Rabbit
Target Protein: BRD2
IR: Immunogen Range:1-50/801
Clonality:
Isotype: IgG
Entrez Gene: 6046
Swiss Prot: P25440
Source: KLH conjugated synthetic peptide derived from human BRD2:1-50/801
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500, IHC-P=1:100-500, ICC=1:50
Cross Reactive Species: (predicted: Human)
For research use only. Not intended for diagnostic or therapeutic use.