Host: Mouse
Target Protein: SNAP25
IR: Immunogen Range:
Clonality:
Isotype: IgG1
Entrez Gene: 6616
Swiss Prot: P60880
Source: KLH conjugated synthetic peptide derived from human SNAP25:
Purification: affinity purified by Protein G
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:20-100
Cross Reactive Species: Human,Mouse,Rat
For research use only. Not intended for diagnostic or therapeutic use.