Host: Rabbit
Target Protein: Caldesmon
IR: Immunogen Range:
Clonality:
Isotype: IgG
Entrez Gene: 800
Swiss Prot: Q05682
Source: KLH conjugated synthetic peptide derived from human Caldesmon:
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jul 2008].
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-1000, IHC-P=1:1000, ICC=1:50-100, IF=1:50-100
Cross Reactive Species: Human,Mouse,Rat
For research use only. Not intended for diagnostic or therapeutic use.