Host: Mouse
Target Protein: Human Tau-4
IR: Immunogen Range:1-441/441
Clonality: Monoclonal
Isotype: IgG3
Entrez Gene: 4137
Swiss Prot: P10636-8
Source: Recombinant Human Tau-4 Protein:1-441/441
Purification: affinity purified by Protein A
Storage: 0.01M PBS(pH7.4) Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
Size: 100ug
Concentration:
Applications: ELISA=1:5000-10000
Cross Reactive Species: (predicted: Human)
For research use only. Not intended for diagnostic or therapeutic use.