Host: Mouse

Target Protein: NF-L

IR: Immunogen Range:1-543/543

Clonality: Monoclonal

Isotype: IgG2a

Entrez Gene: 4747

Swiss Prot: P07196

Source: Recombinant Human NF-L Protein:1-543/543 

Purification: affinity purified by Protein A

Storage: 0.01M PBS(pH7.4)  Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Neurofilament light polypeptide also called NF-L; Neurofilament triplet L protein; 68 kDa neurofilament protein. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The extra mass and high charge density that distinguish the neurofilament proteins from all other intermediate filament proteins are due to the tailpiece extensions. This region may form a charged scaffolding structure suitable for interaction with other neuronal components or ions. NF-L is the most abundant of the three neurofilament proteins and, as the other nonepithelial intermediate filament proteins, it can form homopolymeric 10-nm filaments. Belongs to the intermediate filament family.