Host: Rabbit

Target Protein: ACTHR, Alexa Fluor 750 conjugated

IR: Immunogen Range:67-105/297

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4158

Swiss Prot: Q92506

Source: KLH conjugated synthetic peptide derived from human MC2 receptor:67-105/297 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.