Host: Rabbit
Target Protein: CD74
IR: Immunogen Range:56-279/279
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 972
Swiss Prot: P04233
Source: Recombinant mouse CD74 protein:56-279/279
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Size: 50ul
Concentration: 1mg/ml
Applications: IHC-P=1:400-800, ELISA=1:5000-10000
Cross Reactive Species: Mouse (predicted: Human)
For research use only. Not intended for diagnostic or therapeutic use.