Host: Rabbit

Target Protein: AMPK alpha-1

IR: Immunogen Range:1-207/559

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5562

Swiss Prot: Q13131

Source: Recombinant human AMPK alpha-1 protein :1-207/559 

Purification: affinity purified by Protein A

Storage:  

Background: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]