Host: Rabbit
Target Protein: CCDC98, Alexa Fluor 680 conjugated
IR: Immunogen Range:51-150/409
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 84142
Swiss Prot: Q6UWZ7
Source: KLH conjugated synthetic peptide derived from human CCDC98:51-150/409
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as a central scaffold protein that assembles the various components of the BRCA1-A complex and mediates the recruitment of BRCA1.
Size: 100ul
Concentration: 1mg/ml
Applications:
Cross Reactive Species:
For research use only. Not intended for diagnostic or therapeutic use.