Host: Mouse
Target Protein: Phospho-Histone H3 (Ser10)
IR: Immunogen Range:RK(p-S)TG
Clonality:
Isotype: IgG1/Kappa
Entrez Gene: 8350
Swiss Prot: P68431
Source: KLH conjugated synthesised phosphopeptide derived from human Histone H3 around the phosphorylation site of Ser10:RK(p-S)TG
Purification: Affinity purified by Protein G
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-1:1000, IHC-P=1:100-500, ICC=1:50-1:100
Cross Reactive Species: (predicted: Human,Mouse,Rat)
For research use only. Not intended for diagnostic or therapeutic use.