Host: Mouse
Target Protein: human CD86
IR: Immunogen Range:
Clonality: Monoclonal
Isotype: Mouse IgG1, k
Entrez Gene: 942
Swiss Prot: P42081
Source: :
Purification: Affinity purified by Protein G
Storage: 0.01M TBS(pH=7.4) Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
Size: 100ug
Concentration:
Applications: Flow-Cyt=10ul/Test
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.