Host: Rabbit

Target Protein: Phospho-CD19 (Tyr531)

IR: Immunogen Range:DS(p-Y)EN

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 930

Swiss Prot: P15391

Source: KLH conjugated Synthesised phosphopeptide derived from human CD19 around the phosphorylation site of Tyr531:DS(p-Y)EN 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: CD19 is a transmembrane glycoprotein that is delectively expressed on the cell surface of B-lymphocytes,where it activates intracellular signaling cascades involving both Ras and phosphatidylinositol 3-kinase pathways.Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.