Host: Rabbit

Target Protein: Jak3

IR: Immunogen Range:601-700/1124

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3718

Swiss Prot: P52333

Source: KLH conjugated synthetic peptide derived from human Jak3:601-700/1124 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]