bs-3210R [Primary Antibody]
Rabbit  Anti-phospho-c-Jun (Ser63)  Polyclonal Antibody

Host: Rabbit

Target Protein: phospho-c-Jun (Ser63)

IR: Immunogen Range:LT(p-S)PD

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3725

Swiss Prot: P05412

Source: KLH conjugated Synthesised phosphopeptide derived from human c-Jun around the phosphorylation site of Ser63:LT(p-S)PD 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.

Size: 200ul

Concentration: 1mg/ml

Applications: IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=0.2μg /Test, ELISA=1:5000-10000

Cross Reactive Species: Human,Mouse,Rat (predicted: Dog,Pig,Cow,Rabbit,Sheep)

For research use only. Not intended for diagnostic or therapeutic use.