Host: Rabbit

Target Protein: phospho-HDAC7 (Ser358)

IR: Immunogen Range:TR(p-S)EP

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 51564

Swiss Prot: Q8WUI4

Source: KLH conjugated Synthesised phosphopeptide derived from human HDAC7 around the phosphorylation site of Ser358:TR(p-S)EP 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]