Host: Rabbit
Target Protein: Phospho-SIRT1 (Ser47)
IR: Immunogen Range:R(p-S)PG
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 23411
Swiss Prot: Q96EB6
Source: KLH conjugated Synthesised phosphopeptide derived from human SirT1 around the phosphorylation site of Ser47:R(p-S)PG
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
Size: 200ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=1ug/Test, ELISA=1:5000-10000
Cross Reactive Species: Human,Rat (predicted: Mouse,Dog,Pig,Rabbit)
For research use only. Not intended for diagnostic or therapeutic use.