Host: Rabbit

Target Protein: Phospho-MARCKS (Ser152 + Ser156)

IR: Immunogen Range:RF(p-S)FKK(p-S)FK

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 25603

Swiss Prot: P29966

Source: KLH conjugated synthesised phosphopeptide derived from rat MARCKS around the phosphorylation site of Ser152/156 or Ser159/163(human) :RF(p-S)FKK(p-S)FK 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008]