Host: Rabbit

Target Protein: phospho-Src (Tyr418)

IR: Immunogen Range:NE(p-Y)TA

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6714

Swiss Prot: P12931

Source: KLH conjugated Synthesised phosphopeptide derived from human Src around the phosphorylation site of Tyr418:NE(p-Y)TA 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]