Host: Rabbit

Target Protein: F11R/JAM-A/CD321

IR: Immunogen Range:51-150/299

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 50848

Swiss Prot: Q9Y624

Source: KLH conjugated synthetic peptide derived from human Junctional Adhesion Molecule 1:51-150/299 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Junctional Adhesion Molecule 1 (JAM1) seems to play a role in epithelial tight junction formation. It appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. JAM1 plays a role in regulating monocyte transmigration involved in integrity of the epithelial barrier. JAM1 is also involved in platelet activation.