Host: Rabbit

Target Protein: KDM1/LSD1

IR: Immunogen Range:101-200/852

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 23028

Swiss Prot: O60341

Source: KLH conjugated synthetic peptide derived from human KDM1:101-200/852 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Gene activation and repression is specifically regulated by histone methylation status at distinct lysine residues. Lysine specific demethylase 1 (KDM1/LSD1) is a long-sought histone demethylase that specifically demethylates mono and di methyl histone H3 at K4 and K9. Thus KDM1 is a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor.