Host: Rabbit

Target Protein: HMGCS2

IR: Immunogen Range:101-200/508

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3158

Swiss Prot: P54868

Source: KLH conjugated synthetic peptide derived from human HMGCS2:101-200/508 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: HMGCS2 is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.