Host: Rabbit

Target Protein: ATG16L

IR: Immunogen Range:501-607/607

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 55054

Swiss Prot: Q676U5

Source: KLH conjugated synthetic peptide derived from human ATG16A:501-607/607 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.