Host: Rabbit

Target Protein: GKRP

IR: Immunogen Range:261-360/625

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 2646

Swiss Prot: Q14397

Source: KLH conjugated synthetic peptide derived from human GKRP:261-360/625 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: GCKR is a subfamily member of the SIS (Sugar ISomerase) family of proteins. It is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young.