Host: Rabbit
Target Protein: PITX3
IR: Immunogen Range:231-302/302
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 5309
Swiss Prot: O75364
Source: KLH conjugated synthetic peptide derived from human PITX3:231-302/302
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The transcription factor PITX3 is expressed selectively in the midbrain and regulates the differentiation and survival of dopaminergic neurons. Lack of this factor results in a degeneration similar to that seen in Parkinson's disease. PITX3 is also important in eye developement; mutations of the PITX3 gene have been associated with a familial form of cataracts.
Size: 200ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:50, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Cow,Rat,Mouse,Human (predicted: Rabbit,Horse,Pig,Dog,Chicken)
For research use only. Not intended for diagnostic or therapeutic use.