bs-7056R [Primary Antibody]
Rabbit  Anti-FTO  Polyclonal Antibody
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Host: Rabbit

Target Protein: FTO

IR: Immunogen Range:165-265/505

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 79068

Swiss Prot: Q9C0B1

Source: KLH conjugated synthetic peptide derived from human Protein fatso:165-265/505 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation.
Tissue specificity: Ubiquitously expressed, with relatively high expression in adrenal glands and brain; especially in hypothalamus and pituitary.

Size: 200ul

Concentration: 1mg/ml

Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000

Cross Reactive Species: Human/Mouse/Rat,Rat,Mouse,Human (predicted: Sheep,Rabbit,Horse,Cow,Pig,Dog)

For research use only. Not intended for diagnostic or therapeutic use.

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