Host: Rabbit

Target Protein: CARD8

IR: Immunogen Range:221-320/431

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 22900

Swiss Prot: Q9Y2G2

Source: KLH conjugated synthetic peptide derived from human CARD8:221-320/431 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Inhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases.