Host: Rabbit
Target Protein: Integrin alpha 4
IR: Immunogen Range:551-650/1032
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 3676
Swiss Prot: P13612
Source:
KLH conjugated synthetic peptide derived from human Integrin alpha 4:551-650/1032
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, Flow-Cyt=1μg/Test, ELISA=1:5000-10000
Cross Reactive Species: Human (predicted: Mouse,Rat,Cow,Horse,Rabbit)
For research use only. Not intended for diagnostic or therapeutic use.