Host: Rabbit

Target Protein: AEN

IR: Immunogen Range:1-100/325

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 64782

Swiss Prot: Q8WTP8

Source: KLH conjugated synthetic peptide derived from human Apoptosis enhancing nuclease:1-100/325 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.