Host: Rabbit
Target Protein: NOC2L
IR: Immunogen Range:251-350/749
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 26155
Swiss Prot: Q9Y3T9
Source: KLH conjugated synthetic peptide derived from human NOC2L:251-350/749
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: NOC2L is a transcriptional corepressor with inhibitor of histone acetyltransferase (INHAT) activity. NOC2L or NIR (Novel INHAT Repressor) is ubiquitously expressed throughout embryonic development and adulthood. It is a potent transcriptional corepressor that is not blocked by histone deacetylase inhibitors and is capable of silencing both basal and activator-driven transcription. NOC2L directly binds to nucleosomes and core histones and prevents acetylation by histone acetyltransferases, thus acting as a bona fide INHAT.
Size: 100ul
Concentration: 1mg/ml
Applications: ELISA=1:5000-10000
Cross Reactive Species: (predicted: Human,Mouse,Rat,Pig,Cow,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.