Host: Rabbit

Target Protein: RTN3

IR: Immunogen Range:931-1032/1032

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 10313

Swiss Prot: O95197

Source: KLH conjugated synthetic peptide derived from human NSPL2/RTN3:931-1032/1032 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.